For more information visit:http://uwveterinarycare.wisc.edu
Purpose of study: The study involves intravenous administration of an indenoisoquinoline daily for 5 consecutive days. Blood samples, bone marrow biopsies, and tumor biopsies will be collected prior to treatment and following the first and fifth treatment. The first week of this study will necessitate some (minimum of 2 nights) if not all, overnight boarding at the VMTH. Dogs will then return weekly for re-evaluation and subsequent blood collection (Day 8, 15, 22 and 29). Continuance on study beyond day 29 will be based on response to indenoisoquinoline therapy.