UGA: Trial for Tumor Bearing Dogs

Study details:

Species: Canine

Tumor: Any Tumor Type

For more information:

Purpose of the study: The purpose of this study is to evaluate the safety and efficacy of iniparib, a novel anticancer agent, when given to dogs with cancer. Iniparib has been safely evaluated in human patients with cancer and normal research dogs; however this agent has not been previously used in dogs with cancer either alone or in conjunction with carboplatin. The trial described is divided into three phases, including a dose finding phase for safety and a validation phase for biological assay development (tumor marker evaluation pre and post treatment) as well as a control phase for assessment of carboplatin chemotherapy alone. Dogs must have a confirmed diagnosis of a cancerous solid tumor to be eligible for participation in this study.