Study details:
Species: Canine
Tumor: Any Tumor Type
For more information:http://www.vet.uga.edu/research/clinical/Current%20Clinical%20Trials/webpage%20Lawrence%20iniparib.pdf
Purpose of the study: The purpose of this study is to evaluate the safety and efficacy of iniparib, a novel anticancer agent, when given to dogs with cancer. Iniparib has been safely evaluated in human patients with cancer and normal research dogs; however this agent has not been previously used in dogs with cancer either alone or in conjunction with carboplatin. The trial described is divided into three phases, including a dose finding phase for safety and a validation phase for biological assay development (tumor marker evaluation pre and post treatment) as well as a control phase for assessment of carboplatin chemotherapy alone. Dogs must have a confirmed diagnosis of a cancerous solid tumor to be eligible for participation in this study.